HillcrestLPNPharmacology

Oncology

Tumor promoter, carcinogens, cell cycle, selective toxicity, cytotoxic, metastasis, oncogenes, mitosis, contact inhibition,WBC deficits, stomatitis, and blood dyscrasias

•Decrease cell division
•Some normal cells that divide rapidly: Bone marrow, Intestinal cells, hair follicles

•What is the dosage range between therapeutic range and toxicity?
•What types of effects would bone marrow suppression cause?
•How do you monitor RBCs and WBCs function?
•How would you assure adequate nutrition for chemotherapeutic patient.

•Mitosis and cell cycle G S M stages
•Contact inhibition
•Recognition of self by immune system
•Resistance of cancer cells
•Cytotoxicity- how do we kill them?
•Neoplastic cells- rapidly dividing and active cells
•Metastasis- the ability of neoplastic cells to become mobile and spread


•CBC with differential
•Uric Acid
•Renal functions
•Liver functions


•Cachexia, anorexia loss of appetitie interventions
•Increased fluid intake for dilution and flushing
•Interventions if of child-bearing age
•Blodd dyscrasias as evidenced by WBC, bruising, bleeding